GLP‑1 agonists mimic a “fullness” hormone to curb appetite, slow stomach emptying, and lower blood sugar. In large trials, weekly semaglutide produced ~15% average weight loss over 68 weeks—far beyond older drugs—while improving cardiometabolic risk factors.

Which supplements and interventions truly extend lifespan? This in-depth guide reviews human trial evidence and preclinical data on omega-3s, vitamin D, CoQ10 + selenium, metformin, SGLT2 inhibitors, spermidine, rapamycin, and more. It also covers lifestyle strategies with proven survival benefits—like exercise, Mediterranean diet, blood pressure control, cholesterol lowering, smoking cessation, and vaccination—helping you focus on interventions most likely to add healthy years of life.

Learn about evidence-based supplements proven to support heart function in congestive heart failure. From improving ejection fraction and reducing hospitalizations with Coenzyme Q10 and Omega-3 fatty acids, to enhancing exercise tolerance with Hawthorn extract, these supplements complement medical therapy for better cardiovascular health.

Explore evidence-based supplements that can help improve kidney function and slow the progression of chronic kidney disease. From antioxidant-rich tocotrienol vitamin E to kidney-protective Coenzyme Q10, sodium bicarbonate, astragalus root, and cordyceps mushrooms, find safe, clinically validated options for supporting healthier eGFR levels.

Chronic kidney disease silently affects 800 million people worldwide. This in‑depth guide explains CKD pathophysiology, causes, detection, and thoroughly reviews evidence‑based drugs, supplements, lifestyle changes, and system‑level strategies that can delay kidney failure.