Depression stems from more than just brain chemistry—it can involve nutrient imbalances, stress hormones, and inflammation. This guide highlights science-backed supplements like St. John’s wort, omega-3 fish oil, SAMe, L-methylfolate, and others that target neurotransmitter production or reduce oxidative stress. Each compound has unique benefits and cautionary notes, making them possible allies in supporting mood—even alongside standard medication or therapy.

Looking to tackle elevated LDL or triglycerides without relying solely on prescriptions? This guide reviews clinically supported supplements—from powerful red yeast rice (a natural statin equivalent) and omega-3 fish oil to gentler choices like psyllium fiber or plant sterols. Each works differently to block absorption, boost excretion, or lessen harmful lipids produced by the liver. Use them wisely (and with medical guidance) for a safer path to better heart health.

If you’ve noticed a slow but steady weight gain, you’re not alone—and there’s a world of supplements aiming to help. From caffeine and green tea extract, which both rev up metabolism, to fiber-based glucomannan that may tame cravings, the evidence for each varies. Orlistat remains a heavyweight option for blocking dietary fat, while others like CLA and white kidney bean extract offer milder effects. Ultimately, these tools work best alongside balanced eating and regular activity.

Hypothyroidism can hamper your metabolism, leaving you tired, sluggish, and dealing with slow digestion and dry skin. While medication remains the mainstay treatment, certain nutrients like iodine, selenium, and iron plus herbs such as ashwagandha may provide extra help. Checking levels, spacing supplements from thyroid meds, and picking a supportive multi-supplement formula can boost energy and overall thyroid function.

In this in-depth guide, the author recounts a personal battle with Mast Cell Activation Syndrome (MCAS) and Mastocytosis, revealing how misdiagnoses and repeated ER visits led to a proper diagnosis abroad. The article details key prescription treatments—including H1/H2 blockers, leukotriene inhibitors, and mast cell stabilizers—as well as natural supplements like luteolin, quercetin, DAO, and vitamin C that support symptom management. It’s a call to self-advocacy for those navigating complex immune disorders.